Antigen-capturing Cells Can Masquerade as Memory B Cells

Antigen-capturing Cells Can Masquerade as Memory B Cells

As well as classically defined switched immunoglobulin isotype-expressing B cells, memory B cells are now thought to include IgM-expressing cells and memory cells that lack B cell lineage markers, such as B220 or CD19. We set out to compare the relative importance of memory B cell subsets with an established flow cytometry method to identify antigen-specific cells. After immunization with PE, w...

Transiently antigen primed B cells can generate multiple subsets of memory cells

Memory B cells are long-lived cells that generate a more vigorous response upon recognition of antigen (Ag) and T cell help than naïve B cells and ensure maintenance of durable humoral immunity. Functionally distinct subsets of murine memory B cells have been identified based on isotype switching of BCRs and surface expression of the co-stimulatory molecule CD80 and co-inhibitory molecule PD-L2...

Identification of Antigen - Capturing Cells as Basophils 1

B Lymphocytes as Antigen-Presenting Cells

Elaborating IL - 12 CpG Oligodeoxynucleotides Induce Th 1 Cells B Cells Capturing Antigen Conjugated